Case study

Pioneering a new era of medical discovery

Helping ZEISS build an innovation roadmap to transform the industry’s development of organoids

ZEISS is a global leader in optics and optoelectronics, offering advanced solutions for microscopy and semiconductor manufacturing, amongst others.

Challenge

Bringing a commercial focus to a revolutionary new technology

ZEISS sought to leverage their world-class expertise and tech assets to support the development of organoids, one of the most promising fields in biotech. But they didn’t want to spend years just exploring all of the many possibilities for this new field; their future-oriented Innovation Hub team needed a business focus, and the company needed a way to validate the potential business plan. They came to Board of Innovation to explore new strategic methodologies to commercialize groundbreaking technologies and apply it to organoids.

Strategy

Through technology, understanding customer workflows and what barriers to lower

We teamed up with ZEISS to design a repeatable, strategic methodology based on customer pain points and market trends to explore and narrow down disruptive technologies, identify use cases, and map and select the right partnership models.

We applied this methodology to the organoids space by understanding customer workflows and bottlenecks, to identify short-term commercial applications

Sample deliverable generated by AI for illustrative purposes only.

Outcome

A multi-year roadmap with clear market entry points

The ZEISS Innovation Hub team now has a strong vision for their role in the future of organoids, made actionable with clear market entry point recommendations based on customer needs.

Our work with ZEISS has opened up exciting possibilities for the future medical research, and helped the company consider strategies how it might expand its competencies and position itself within an ecosystem of multiple players.

Sample deliverable generated by AI for illustrative purposes only.

A roadmap to get new medical treatments for all of us, faster and at a lower cost

Case study at a glance – Maria Putilina | Business Designer

Challenge

Bringing a commercial focus to a revolutionary new technology

ZEISS is a global market leader in optical technologies, e.g. for medical and scientific devices (imaging, microscopes) and microchips (lithography optics). They sought to leverage their expertise and tech assets to support the development of organoids (organ-specific tissue produced in vitro), one of the most promising fields in biotech. But they didn’t want to spend years just exploring all of the many possibilities for this new field; their talented R&D team needed a business focus.

ZEISS was struggling with a strategic question shared by many other R&D-heavy companies: what fundamentally disruptive technologies should we be paying attention to, and developing new research, technologies and products around? How do we know if we're making the right decision? And once we've made a decision, how do we make sure we're doing this in the most strategic way possible? How do we avoid spending decades before getting to any profitable products and services? How can we be more effective with our resources to create and validate a coherent plan to deploy potentially disruptive technologies?

Strategy

Understanding customer workflows and barriers to lower through technology

We helped ZEISS consider the possible futures for organoids – what might be possible 10 or 15 years from now – and build a vision for what role the company wanted to play. They had already done a lot of research to define the space, and so we worked with them to put some order in all the data that they had and use it to help craft a vision that is suited to the company’s strategic position and the broader ecosystem. Then we helped them consider the potential entry points and roadmap for the company to start achieving that vision.

An important part of this was to help them define and narrow down the different technologies that they could leverage in order to enter this space; then to be even more precise in finding what the company could build on the top of those technologies.

For organoid researchers, one pain point has been the lack of integrated solutions. (...) So the integration is still painstakingly manual. And if something goes wrong anywhere in this process you might have compromised an entire month’s work. That’s especially a problem for organoid research where replicating results over and over again is essential.

Pierpaolo Padula, principal healthcare consultant at Board of Innovation

Because no single company has all the core competencies to fulfill the potential for organoids, we knew that ZEISS needed to decide not only how to expand its own competencies, but also how it wanted to be part of an ecosystem with multiple players. So we also worked with them to identify the right partnership model.

To understand how the market is evolving, an important part of our work was understanding potential customer workflow bottlenecks and how they are overcoming these pain points by leveraging currently available technologies. Based on this understanding, we began to probe whether some of the ideas that ZEISS’ R&D team were exploring create enough added value.

To get to one approved drug, thousands of compounds have to be screened. And the width of this funnel is what really determines the cost and the time to market. So the earlier in the process that we can get rid of compounds, the better it is for saving money and time

Outcome

A multi-year roadmap with clear market entry point

Organoids have been a research focus of our microscopy customers for a long time. With growing maturity, these model systems will have a profound impact on adjacent markets. BOI helped us to turn a vague sense of opportunity into concrete scenarios and entry points to pursue.

Dr. Kai Wicker, Head of the ZEISS Inno-Hub Dresden

As part of a potential multi-year roadmap for organoid tech that we helped the ZEISS research team develop, we identified a possible viable short-term commercial application: using imaging technologies to enable the scaling of production and evaluation of organoids at a level of quality good enough for medical research (finding drug targets and testing drug candidates)

Sample deliverable generated by AI for illustrative purposes only.

With the help of innovative solutions, organoids have the potential to complement the preclinical and clinical trials, leading to faster drug development timelines and bringing newer treatments to patients faster and at a lower cost.

5k - 10k

The number of compounds that typically have to be screened to get a single FDA-approved drug

As animal testing is increasingly restricted globally, organoids offer a more ethical and efficient alternative for drug development. For example, 42 countries, including the 27 member states of the EU, AUS, and UK, have banned animal testing. The FDA has also recently announced it will no longer require animal tests before human drug trials.

The ZEISS Inno Hub team is exploring how organoids can complement clinical studies, offering new insights and efficiencies to the process. While replacing human trials is not the goal, the promise of faster drug development timelines and cost savings make organoids a promising area of research for the future of healthcare.

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